Investigadores de la UMH desarrollan un método para tratar enfermedades oculares con material genético

725 comentarios / Por /

Un equipo de investigadores de la Universidad Miguel Hernández (UMH) de Elche (Alicante), en colaboración con profesores de la Universidad del País Vasco (UPV), han desarrollado una metodología para tratar mediante material genético enfermedades oculares como la retinosis pigmentaria, la degeneración macular, la retinosquisis o la amaurosis congénita de Leber, según ha informado en un comunicado la institución académica.

   El profesor de la UMH y director de la cátedra Egara, Eduardo Fernández, lidera la investigación, que se realiza en colaboración con el grupo de la profesora de la UPV, Alicia Rodríguez. Además, Fernández es investigador del Instituto de Bioingeniería de la UMH y del Centro de Investigación Biomédica en Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN).

   Los investigadores han indicado que «la única forma efectiva de llevar material genético al interior de las células –para tratar de corregir problemas genéticos– es utilizar un virus específicamente diseñado para esta tarea», sin embargo, esta aproximación presenta algunos problemas de seguridad «y una gran limitación en cuanto al tamaño del material genético a transportar».

   El objetivo principal de esta línea de trabajo conjunta entre la Cátedra de Investigación Bidons Egara de la UMH y el Laboratorio de Farmacia y Tecnología Farmacéutica de la UPV ha sido «el desarrollo de nuevos vectores no virales para transportar material genético al interior de diversos tipos de células de la retina».

   Con ello, «se pretende modular la expresión de varias proteínas que se pueden encontrar alteradas en diversas patologías de la retina» con el objetivo de poder revertir el problema, «al menos parcialmente», han subrayado.

   Para tal fin, los investigadores han utilizado nanopartículas sólidas lipídicas que han sido modificadas especialmente para facilitar su incorporación a las células de la retina y que, además, incorporan moléculas directoras que permiten llevar estas nanopartículas directamente hacia el núcleo celular.

   Esta nueva tecnología se ha probado con éxito en animales de investigación en experimentos realizados ‘in vitro’ e ‘in vivo’, y los investigadores han advertido de que, «aunque los resultados preliminares son muy prometedores, todavía queda mucho trabajo por hacer».

   Además, han señalado que «es muy importante avanzar poco a poco y no crear falsas expectativas», ya que todavía «no se sabe si la transfección se mantiene durante largos periodos de tiempo, algo fundamental para que este tipo de terapia génica sea un tratamiento efectivo para este grupo de enfermedades».

RECONOCIMIENTO INTERNACIONAL

   Este trabajo ha sido publicado en el último número de la revista ‘Human Gene Therapy’, y desde el departamento de Genética del Instituto de Oftalmología del University College de Londres han calificado la investigación como «una de las líneas de trabajo más prometedoras en este campo». La Cátedra de Investigación Bidons Egara de la UMH apoya la investigación, la formación universitaria y la difusión del conocimiento de las patologías visuales en general y de la retinosis pigmentaria en particular.

   Desde su creación en el año 2005, mediante el apoyo y mecenazgo de la Empresa Bidons Egara de Terrasa (Barcelona), su principal objetivo se centra en ayudar a identificar los mecanismos comunes que se encuentran en muchas de las patologías degenerativas de la retina y en potenciar el apoyo científico y técnico a estas investigaciones. El fin del proyecto es contribuir al desarrollo de nuevas alternativas terapéuticas que puedan ayudar a mejorar la calidad de vida de las personas afectadas por estas enfermedades.

Fuente: Europapress

725 comentarios en “Investigadores de la UMH desarrollan un método para tratar enfermedades oculares con material genético”

  24. irestore coupon

    Oh my goodness! Awesome article dude! Many thanks, However I am encountering troubles with your RSS. I don’t know why I can’t join it. Is there anybody having the same RSS problems? Anybody who knows the answer will you kindly respond? Thanks!!

  29. one88.party

    I’m amazed, I have to admit. Seldom do I come across a blog that’s both educative and amusing, and without a doubt, you’ve hit the nail on the head. The issue is an issue that not enough men and women are speaking intelligently about. Now i’m very happy I came across this during my search for something concerning this.

  40. lucky88.design

    I seriously love your website.. Pleasant colors & theme. Did you create this site yourself? Please reply back as I’m trying to create my own blog and want to learn where you got this from or exactly what the theme is named. Thanks.

  43. b52club.casa

    Good blog you have here.. It’s difficult to find high-quality writing like yours nowadays. I truly appreciate individuals like you! Take care!!

  103. porn

    I love reading an article that can make people think. Also, many thanks for allowing me to comment.

  125. New Balance Sneakers

    I’m impressed, I have to admit. Rarely do I encounter a blog that’s equally educative and engaging, and without a doubt, you’ve hit the nail on the head. The issue is an issue that not enough folks are speaking intelligently about. I am very happy that I found this during my hunt for something concerning this.

  156. xxx mom son fuck HD movies

    I blog frequently and I truly thank you for your content. The article has really peaked my interest. I will book mark your blog and keep checking for new details about once a week. I subscribed to your RSS feed as well.

  185. pornhub

    After looking over a few of the blog articles on your web page, I seriously appreciate your technique of writing a blog. I saved as a favorite it to my bookmark webpage list and will be checking back in the near future. Take a look at my website as well and tell me how you feel.

  203. Man88

    May I simply just say what a comfort to uncover somebody who really knows what they are discussing on the net. You certainly understand how to bring a problem to light and make it important. More people have to read this and understand this side of your story. I can’t believe you aren’t more popular since you definitely have the gift.

  217. aev99 online

    Spot on with this write-up, I seriously think this site needs a great deal more attention. I’ll probably be returning to read through more, thanks for the info!

  227. oxbet

    Your style is very unique compared to other folks I have read stuff from. I appreciate you for posting when you have the opportunity, Guess I will just book mark this blog.

  231. da88

    Everything is very open with a really clear explanation of the issues. It was truly informative. Your site is very useful. Thanks for sharing.

  232. redirected here

    Spot on with this write-up, I absolutely feel this site needs much more attention. I’ll probably be back again to read through more, thanks for the information!

  296. Anime

    Good day! I simply wish to give you a big thumbs up for your excellent information you have here on this post. I am returning to your site for more soon.

  303. Móc lồn em sinh viên

    Hello there! This post could not be written much better! Looking through this post reminds me of my previous roommate! He constantly kept talking about this. I will send this post to him. Pretty sure he’s going to have a very good read. Thanks for sharing!

  304. porn

    The next time I read a blog, Hopefully it doesn’t disappoint me as much as this one. After all, I know it was my choice to read, however I actually thought you would probably have something interesting to talk about. All I hear is a bunch of moaning about something you could fix if you were not too busy looking for attention.

  305. sex trẻ em

    Right here is the perfect web site for anybody who hopes to find out about this topic. You know so much its almost tough to argue with you (not that I really will need to…HaHa). You definitely put a fresh spin on a topic that has been written about for decades. Excellent stuff, just great.

  313. 인천 쓰리노

    You’re so awesome! I don’t think I’ve truly read something like this before. So wonderful to discover someone with a few original thoughts on this subject. Really.. thanks for starting this up. This web site is something that is needed on the internet, someone with a little originality.

  318. 68 Game Bài

    Hi, I do believe your website may be having browser compatibility issues. When I look at your blog in Safari, it looks fine however, when opening in IE, it’s got some overlapping issues. I just wanted to give you a quick heads up! Other than that, great website.

  321. one88

    Spot on with this write-up, I really think this site needs a great deal more attention. I’ll probably be back again to read more, thanks for the advice.

  322. 7club

    That is a great tip particularly to those new to the blogosphere. Simple but very precise information… Many thanks for sharing this one. A must read post.

  338. 89bet

    It’s hard to come by well-informed people about this subject, however, you sound like you know what you’re talking about! Thanks

  347. Bugis chiropractor

    Hi, I do believe this is a great blog. I stumbledupon it 😉 I am going to come back yet again since i have book-marked it. Money and freedom is the best way to change, may you be rich and continue to guide others.

  363. Lototo

    After I initially commented I seem to have clicked the -Notify me when new comments are added- checkbox and from now on whenever a comment is added I get four emails with the exact same comment. Is there a means you can remove me from that service? Thanks a lot.

  367. vpn推荐

    Hello there! This article could not be written any better! Looking at this post reminds me of my previous roommate! He continually kept preaching about this. I’ll send this post to him. Pretty sure he will have a great read. I appreciate you for sharing!

  418. SODO

    This is the perfect website for anyone who would like to understand this topic. You understand a whole lot its almost hard to argue with you (not that I really will need to…HaHa). You certainly put a fresh spin on a topic that has been discussed for many years. Wonderful stuff, just great.

  425. แอม มิยาบิvk

    I blog frequently and I genuinely thank you for your content. Your article has truly peaked my interest. I will take a note of your site and keep checking for new information about once a week. I subscribed to your RSS feed as well.

  441. kashpo napolnoe_jgSi

    большие высокие кашпо kashpo-napolnoe-msk.ru – kashpo-napolnoe-msk.ru .

  444. fiverr

    Way cool! Some very valid points! I appreciate you penning this post plus the rest of the website is also very good.

  486. Source

    May I just say what a comfort to find an individual who really understands what they are discussing on the internet. You definitely understand how to bring a problem to light and make it important. More and more people should read this and understand this side of your story. I was surprised you aren’t more popular given that you certainly have the gift.

  501. 789win

    I really love your blog.. Great colors & theme. Did you develop this site yourself? Please reply back as I’m trying to create my own blog and would like to know where you got this from or just what the theme is named. Thanks!

  508. kashpo napolnoe_hwSr

    напольные горшки для цветов купить интернет магазин http://www.kashpo-napolnoe-rnd.ru/ – напольные горшки для цветов купить интернет магазин .

  511. Good88

    Aw, this was an extremely nice post. Finding the time and actual effort to create a top notch article… but what can I say… I put things off a lot and never manage to get anything done.

  518. ragnarok online with gepard

    I was more than happy to find this website. I wanted to thank you for ones time for this fantastic read!! I definitely liked every part of it and I have you book marked to look at new information on your web site.

  553. hacklink satın

    I have to thank you for the efforts you’ve put in writing this blog. I’m hoping to see the same high-grade blog posts by you in the future as well. In fact, your creative writing abilities has encouraged me to get my very own site now 😉

  595. 33win

    Excellent blog you’ve got here.. It’s difficult to find high-quality writing like yours these days. I seriously appreciate individuals like you! Take care!!

  596. SaketWahi

    I must thank you for the efforts you’ve put in writing this blog. I really hope to check out the same high-grade content from you later on as well. In truth, your creative writing abilities has inspired me to get my very own website now 😉

  600. sa88

    Next time I read a blog, Hopefully it doesn’t disappoint me just as much as this particular one. I mean, Yes, it was my choice to read through, nonetheless I genuinely believed you would have something useful to talk about. All I hear is a bunch of complaining about something you can fix if you weren’t too busy looking for attention.

  608. SODO

    This is a topic that’s near to my heart… Many thanks! Where can I find the contact details for questions?

  662. mm99

    I’m impressed, I have to admit. Rarely do I come across a blog that’s both equally educative and engaging, and let me tell you, you’ve hit the nail on the head. The issue is an issue that not enough people are speaking intelligently about. I’m very happy I came across this during my search for something concerning this.

  671. 33win

    That is a great tip especially to those fresh to the blogosphere. Short but very accurate information… Many thanks for sharing this one. A must read article.

  679. 파라존 코리아 카지노

    Right here is the right blog for anybody who wishes to find out about this topic. You realize a whole lot its almost tough to argue with you (not that I actually would want to…HaHa). You certainly put a new spin on a topic which has been discussed for years. Wonderful stuff, just excellent.

  682. MM99

    Your style is so unique compared to other people I’ve read stuff from. Thank you for posting when you’ve got the opportunity, Guess I will just book mark this site.

  689. hepato burn official website buy online

    I have to thank you for the efforts you’ve put in writing this site. I’m hoping to view the same high-grade blog posts by you in the future as well. In fact, your creative writing abilities has encouraged me to get my own, personal blog now 😉

  705. download video tiktok

    I seriously love your website.. Great colors & theme. Did you create this website yourself? Please reply back as I’m planning to create my own site and want to find out where you got this from or what the theme is called. Thanks!

  721. Link vào WW88

    Good post. I learn something new and challenging on blogs I stumbleupon every day. It’s always exciting to read articles from other writers and practice a little something from their sites.

Deja un comentario

Tu dirección de correo electrónico no será publicada. Los campos obligatorios están marcados con *

Scroll al inicio
Powered by  GDPR Cookie Compliance
Resumen de privacidad

Esta web utiliza cookies para que podamos ofrecerte la mejor experiencia de usuario posible. La información de las cookies se almacena en tu navegador y realiza funciones tales como reconocerte cuando vuelves a nuestra web o ayudar a nuestro equipo a comprender qué secciones de la web encuentras más interesantes y útiles.

Puedes revisar nuestra página de privacidad y cookies.