Investigadores de la UMH desarrollan un método para tratar enfermedades oculares con material genético

689 comentarios / Por /

Un equipo de investigadores de la Universidad Miguel Hernández (UMH) de Elche (Alicante), en colaboración con profesores de la Universidad del País Vasco (UPV), han desarrollado una metodología para tratar mediante material genético enfermedades oculares como la retinosis pigmentaria, la degeneración macular, la retinosquisis o la amaurosis congénita de Leber, según ha informado en un comunicado la institución académica.

   El profesor de la UMH y director de la cátedra Egara, Eduardo Fernández, lidera la investigación, que se realiza en colaboración con el grupo de la profesora de la UPV, Alicia Rodríguez. Además, Fernández es investigador del Instituto de Bioingeniería de la UMH y del Centro de Investigación Biomédica en Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN).

   Los investigadores han indicado que «la única forma efectiva de llevar material genético al interior de las células –para tratar de corregir problemas genéticos– es utilizar un virus específicamente diseñado para esta tarea», sin embargo, esta aproximación presenta algunos problemas de seguridad «y una gran limitación en cuanto al tamaño del material genético a transportar».

   El objetivo principal de esta línea de trabajo conjunta entre la Cátedra de Investigación Bidons Egara de la UMH y el Laboratorio de Farmacia y Tecnología Farmacéutica de la UPV ha sido «el desarrollo de nuevos vectores no virales para transportar material genético al interior de diversos tipos de células de la retina».

   Con ello, «se pretende modular la expresión de varias proteínas que se pueden encontrar alteradas en diversas patologías de la retina» con el objetivo de poder revertir el problema, «al menos parcialmente», han subrayado.

   Para tal fin, los investigadores han utilizado nanopartículas sólidas lipídicas que han sido modificadas especialmente para facilitar su incorporación a las células de la retina y que, además, incorporan moléculas directoras que permiten llevar estas nanopartículas directamente hacia el núcleo celular.

   Esta nueva tecnología se ha probado con éxito en animales de investigación en experimentos realizados ‘in vitro’ e ‘in vivo’, y los investigadores han advertido de que, «aunque los resultados preliminares son muy prometedores, todavía queda mucho trabajo por hacer».

   Además, han señalado que «es muy importante avanzar poco a poco y no crear falsas expectativas», ya que todavía «no se sabe si la transfección se mantiene durante largos periodos de tiempo, algo fundamental para que este tipo de terapia génica sea un tratamiento efectivo para este grupo de enfermedades».

RECONOCIMIENTO INTERNACIONAL

   Este trabajo ha sido publicado en el último número de la revista ‘Human Gene Therapy’, y desde el departamento de Genética del Instituto de Oftalmología del University College de Londres han calificado la investigación como «una de las líneas de trabajo más prometedoras en este campo». La Cátedra de Investigación Bidons Egara de la UMH apoya la investigación, la formación universitaria y la difusión del conocimiento de las patologías visuales en general y de la retinosis pigmentaria en particular.

   Desde su creación en el año 2005, mediante el apoyo y mecenazgo de la Empresa Bidons Egara de Terrasa (Barcelona), su principal objetivo se centra en ayudar a identificar los mecanismos comunes que se encuentran en muchas de las patologías degenerativas de la retina y en potenciar el apoyo científico y técnico a estas investigaciones. El fin del proyecto es contribuir al desarrollo de nuevas alternativas terapéuticas que puedan ayudar a mejorar la calidad de vida de las personas afectadas por estas enfermedades.

Fuente: Europapress

689 comentarios en “Investigadores de la UMH desarrollan un método para tratar enfermedades oculares con material genético”

  15. Tubidy

    This is a topic that is near to my heart… Best wishes! Exactly where can I find the contact details for questions?

  39. fast income

    I want to to thank you for this great read!! I definitely enjoyed every little bit of it. I have got you book-marked to check out new things you post…

  70. baca disini

    The next time I read a blog, I hope that it won’t fail me just as much as this particular one. After all, I know it was my choice to read through, but I actually believed you’d have something helpful to talk about. All I hear is a bunch of crying about something that you could possibly fix if you weren’t too busy seeking attention.

  109. Snaptik

    Everything is very open with a very clear description of the challenges. It was really informative. Your website is extremely helpful. Thank you for sharing!

  153. QH88 BET

    I absolutely love your website.. Great colors & theme. Did you make this website yourself? Please reply back as I’m hoping to create my own personal site and want to learn where you got this from or what the theme is called. Thank you!

  171. Ibomma

    Way cool! Some very valid points! I appreciate you writing this post and also the rest of the website is very good.

  176. supplements

    You have made some good points there. I checked on the net for additional information about the issue and found most individuals will go along with your views on this website.

  185. look at this site

    Nice post. I learn something new and challenging on sites I stumbleupon everyday. It’s always useful to read articles from other authors and use a little something from other web sites.

  196. BNB buggy tours

    Hello, I do think your web site might be having web browser compatibility issues. When I take a look at your blog in Safari, it looks fine however, if opening in Internet Explorer, it’s got some overlapping issues. I just wanted to give you a quick heads up! Aside from that, excellent site.

  198. gamdom giriş

    May I just say what a relief to uncover someone that actually knows what they’re talking about over the internet. You certainly know how to bring a problem to light and make it important. More people ought to look at this and understand this side of the story. I was surprised you are not more popular since you most certainly have the gift.

  207. คลิปหลุดสายฝน

    An outstanding share! I’ve just forwarded this onto a co-worker who was doing a little research on this. And he in fact ordered me dinner simply because I found it for him… lol. So allow me to reword this…. Thanks for the meal!! But yeah, thanx for spending time to discuss this subject here on your site.

  214. หีปลาย

    Good post. I learn something totally new and challenging on websites I stumbleupon every day. It’s always interesting to read content from other authors and use a little something from other web sites.

  247. cheap viagra

    I blog frequently and I seriously thank you for your content. This article has really peaked my interest. I will bookmark your blog and keep checking for new details about once a week. I opted in for your RSS feed too.

  251. Philliptow

    В данной обзорной статье представлены интригующие факты, которые не оставят вас равнодушными. Мы критикуем и анализируем события, которые изменили наше восприятие мира. Узнайте, что стоит за новыми открытиями и как они могут изменить ваше восприятие реальности.
    Ознакомиться с деталями – https://nakroklinikatest.ru/

  291. bet88vip.bet

    Having read this I believed it was rather informative. I appreciate you finding the time and effort to put this information together. I once again find myself personally spending a significant amount of time both reading and leaving comments. But so what, it was still worth it!

  295. gamebaitop10

    I really love your website.. Great colors & theme. Did you make this web site yourself? Please reply back as I’m attempting to create my very own website and would love to know where you got this from or exactly what the theme is named. Thank you.

  301. m88

    I have to thank you for the efforts you’ve put in penning this blog. I am hoping to view the same high-grade content by you later on as well. In truth, your creative writing abilities has motivated me to get my own, personal website now 😉

  308. go88

    After looking at a handful of the articles on your site, I really like your technique of blogging. I book marked it to my bookmark website list and will be checking back in the near future. Please visit my web site too and let me know your opinion.

  317. seo firms near me

    An outstanding share! I have just forwarded this onto a coworker who had been conducting a little homework on this. And he actually bought me dinner simply because I found it for him… lol. So let me reword this…. Thank YOU for the meal!! But yeah, thanx for spending the time to talk about this matter here on your site.

  334. SODO

    Hi there! I could have sworn I’ve visited this site before but after looking at many of the articles I realized it’s new to me. Anyhow, I’m definitely happy I stumbled upon it and I’ll be bookmarking it and checking back frequently.

  364. boston law group

    I blog frequently and I truly appreciate your content. The article has really peaked my interest. I am going to take a note of your blog and keep checking for new details about once a week. I subscribed to your Feed too.

  409. Mexican coffee Canada

    I’m amazed, I have to admit. Rarely do I come across a blog that’s equally educative and entertaining, and without a doubt, you’ve hit the nail on the head. The problem is an issue that not enough men and women are speaking intelligently about. I’m very happy that I stumbled across this in my search for something regarding this.

  422. x8

    energetika.us.com là nền tảng kiến thức giá trị cho cộng đồng kỹ thuật

  435. dewa cash

    You should be a part of a contest for one of the most useful blogs on the internet. I most certainly will recommend this website!

  460. most used steroid

    Nearly every sort of steroid available in our store can be utilized to spice up your body’s performance and
    pace up your recovery from accidents, burns, and fractures.
    Additionally, during the consumption of anabolic steroids, catabolic processes lower, and recovery
    after exercise improves. Absolutely all physical qualities change for the better,
    that is what is important in sports activities. Our store for an extended time helps athletes purchase
    high-quality pharmacology. The inexpensive prices of the purchase
    steroids Australia on the location are for genuine products, and you may
    contact our customer service employees with any questions via the Contact Us section of our
    website. The alternative of what bulking steroids to contemplate when creating a cycle depends on each particular person and his/her desired objective.

    Being knowledgeable of how steroids work can maximize their
    potential when stacked in a cycle.
    From the ratio of «price-performance» they are considerably inferior to the amino acids.
    Earlier Than buying any medication at our specialized sports pharmacology
    store, we give you a free full session. Keep In Mind that each steroid has its own dosages,
    so it’s as much as you how safe and efficient your slicing cycles might be.
    Anabolic steroids are artificial, or human made variations of the male sex hormone,
    testosterone.
    A well-balanced nutrition plan includes a combine of lean proteins, healthy
    fats, and complex carbohydrates to fuel your physique and boost your vitality levels.
    As you embark in your journey with legal steroids, it’s vital to
    follow the recommended dosage and instructions for optimal
    results. Usually speaking, these supplements are finest used
    with a proper diet and common exercise routine.
    Consistency is key, so make sure to take the merchandise as instructed for the
    appropriate length of time—usually, a minimum of
    eight weeks. These shops typically have educated staff
    members who can information clients toward the best supplements
    for his or her objectives. In addition to this, the stores often provide promotional offers and discounts on their products, which
    may help prospects save money while achieving their fitness targets.

    Trainers are often hesitant to discuss steroids, particularly with clients they do not know properly.
    ● Decreased testosterone production – reversed with numerous substances during post-cycle therapy (PCT).
    In most instances, the consumer only sees placebo results, resulting in wasted time and lost money.
    In the worst cases, these so-called ‘safe substitutes’
    may end up in severe unwanted effects, which are conveniently
    left out of their descriptions. And even if you’re not certainly one of these people, there are still specific guidelines you must follow to
    make sure secure steroid use. Injecting hormones immediately
    into the physique is a very quick and environment friendly
    way to administer them without risking injury to the liver.
    However raising hormone ranges too shortly can cause uncontrollable
    issues.
    On the opposite hand, the medicine are saving many
    lives, so you want to balance between the benefits and attainable harmful effects.
    Truly, steroids in therapeutic doses produce little or no unwanted side effects.

    It sometimes seems naturally maturing in teenagers, and a small portion of
    males.
    Steroids are notably well-liked in sports activities like bodybuilding and powerlifting because of these results.
    Anabolic steroids have achieved excessive leads to
    powerlifting, bodybuilding, and different energy sports activities since using
    how a lot do steroids price pharmacology. It is the commonest technique
    of anabolic steroid purchase, in-fact millions upon hundreds of thousands purchase anabolic steroids on-line every single year and it shows
    no true signal of slowing down.
    Prime Male can be recognized for its fat-burning capabilities, permitting customers to achieve a lean, toned physique
    in a shorter timeframe. Its easy-to-use capsule form makes incorporating the
    supplement into a every day routine hassle-free, and because it’s made in FDA-inspected amenities;
    users can belief within the quality and safety of the product.
    You can even purchase injectable steroids on mega-steroids, this website is really certain and the place you can sometimes get discount, so we suggest you
    to go to the site for extra informations about
    that. As we mentioned, our favorite place for genuine, high-quality steroids is MonsterSteroids.org.
    So now you have a dependable supply to show to whenever
    you’re able to make a purchase order. Our goal with this
    information was to arrange you with the essential details wanted to buy steroids in the Usa on-line
    safely and effectively. We hope you discovered our
    ideas useful, and that they’ll enhance your confidence in navigating the world
    of on-line steroid sources.
    Remember, the accountable use of Anavar goes hand in hand with appropriate dosages,
    cycle lengths, and post-cycle therapy (PCT) protocols.
    Monitoring your body’s response, managing potential side effects, and prioritizing overall well-being are key elements of using Anavar safely and effectively.
    By making knowledgeable selections, in search of guidance, and following greatest practices, you can optimize your Anavar experience and
    work in direction of attaining your required health and
    performance targets. If you’re contemplating steroids for bodybuilding
    or efficiency enhancement, seek the guidance of with healthcare professionals to grasp the authorized alternate options and decrease dangers to your well being.
    Prohormones are precursor compounds that transform into lively anabolic hormones
    in your body. Skilled sportspeople and amateurs alike are more and more inquiring about using legally obtainable anabolic steroids.

    Right Here are a number of the risks you would face
    when shopping for steroids on-line. Getting a health care
    provider’s prescription is probably certainly one of the most
    reliable methods to make sure that you just’re buying pharmaceutical-grade steroids.
    Nonetheless, buying medical steroids and not utilizing a proper medical
    cause is unusual. If you don’t undergo from one of these
    circumstances, discovering a doctor to prescribe steroids goes
    to be troublesome. If you have been tempted to buy a «legal substitute»
    over an precise steroid, permit us to give you some helpful
    recommendation. First, think about reading real opinions and results of
    individuals that have already purchased and tried the product by
    typing «Reddit product name» into Google. There you’ll discover
    plenty of discussions between unhappy prospects who’ve sadly misplaced their money and
    time via deceitful complement suppliers.

    If you need REAL steroids for sale, NEVER buy from basicstero, they don’t have real steroids.

    When speak about USA domestic shipping, Domestic-supply.com (the
    actual one) is taken into account by most used steroid industry specialists
    as the best brand to purchase domestic steroids for sale in the world.
    You can see on the forums it’s regularly
    discussed that D-S and Greg are the most effective in home transport.

    Biomed works with the most elite manufacturers and producers in Canada.
    All our merchandise are created with the best quality materials and third get together lab tested.
    This consists of injectables, tablets, sarms, peptides, fat-burners, HGH, anti-estrogen, and extra.

    At BioMed, we take the safety of our prospects very seriously
    and put the utmost precedence on privacy.

  495. https://crypto30x.com/

    The very next time I read a blog, I hope that it doesn’t fail me just as much as this one. I mean, I know it was my choice to read through, but I really thought you’d have something useful to talk about. All I hear is a bunch of crying about something you can fix if you were not too busy searching for attention.

  509. https://myfastbroker.com/

    I seriously love your website.. Pleasant colors & theme. Did you make this web site yourself? Please reply back as I’m attempting to create my own personal blog and would love to find out where you got this from or exactly what the theme is called. Kudos!

  512. early childcare education

    I blog often and I seriously thank you for your information. The article has really peaked my interest. I am going to book mark your blog and keep checking for new information about once a week. I subscribed to your Feed too.

  514. Reno Reike Sessions

    Nice post. I learn something totally new and challenging on blogs I stumbleupon on a daily basis. It will always be useful to read through content from other writers and practice something from their web sites.

  524. Business credit

    You made some good points there. I looked on the web to find out more about the issue and found most people will go along with your views on this site.

  543. Rebbevof

    Long-distance relationships were a challenge for Joe until he could rely on cheap viagra. True change isn’t instant – it’s patiently built through daily belief and action.

  551. zowin

    It’s hard to find knowledgeable people about this subject, but you seem like you know what you’re talking about! Thanks

  556. 강남구구단

    Hi there, I do think your website might be having browser compatibility issues. When I look at your website in Safari, it looks fine however, when opening in I.E., it’s got some overlapping issues. I simply wanted to give you a quick heads up! Other than that, fantastic blog!

  558. BLV GÀ LỬA

    Having read this I believed it was rather informative. I appreciate you finding the time and energy to put this short article together. I once again find myself personally spending a significant amount of time both reading and posting comments. But so what, it was still worthwhile!

  563. manclub

    Your style is so unique compared to other people I’ve read stuff from. Thank you for posting when you have the opportunity, Guess I will just book mark this page.

  565. bot88

    Hi, I do think this is a great site. I stumbledupon it 😉 I’m going to return once again since I bookmarked it. Money and freedom is the best way to change, may you be rich and continue to guide others.

  570. BLV GÀ RỪNG

    I seriously love your website.. Excellent colors & theme. Did you develop this web site yourself? Please reply back as I’m planning to create my own personal site and would like to know where you got this from or exactly what the theme is called. Thanks!

  582. 강남퍼펙트

    Spot on with this write-up, I really believe that this site needs far more attention. I’ll probably be back again to see more, thanks for the info!

  604. Coaching

    After exploring a number of the blog articles on your website, I really appreciate your way of blogging. I book-marked it to my bookmark website list and will be checking back soon. Take a look at my web site too and let me know how you feel.

  609. nervovive

    Howdy! I could have sworn I’ve been to this blog before but after going through a few of the articles I realized it’s new to me. Nonetheless, I’m definitely delighted I stumbled upon it and I’ll be book-marking it and checking back regularly!

  619. Dune Buggy Dubai

    Everything is very open with a very clear explanation of the challenges. It was truly informative. Your website is extremely helpful. Thank you for sharing.

  624. us citizen working in singapore

    You’re so interesting! I do not suppose I have read anything like that before. So wonderful to find someone with unique thoughts on this subject. Seriously.. many thanks for starting this up. This website is one thing that is needed on the web, someone with a bit of originality.

Deja un comentario

Tu dirección de correo electrónico no será publicada. Los campos obligatorios están marcados con *

Scroll al inicio
Powered by  GDPR Cookie Compliance
Resumen de privacidad

Esta web utiliza cookies para que podamos ofrecerte la mejor experiencia de usuario posible. La información de las cookies se almacena en tu navegador y realiza funciones tales como reconocerte cuando vuelves a nuestra web o ayudar a nuestro equipo a comprender qué secciones de la web encuentras más interesantes y útiles.

Puedes revisar nuestra página de privacidad y cookies.